1.方法一:win32实现通知

import win32api, win32con, win32gui
import time

class Taskbar:
    def __init__(self):
        self.visible = 0
        message_map = {
            win32con.WM_DESTROY: self.onDestroy,
        }

        # Register the Window class.
        wc = win32gui.WNDCLASS()
        hinst = wc.hInstance = win32api.GetModuleHandle(None)
        wc.lpszClassName = "PythonTaskbar"

        wc.lpfnWndProc = message_map
        classAtom = win32gui.RegisterClass(wc)

        # Create the Window.
        style = win32con.WS_OVERLAPPED | win32con.WS_SYSMENU
        exStyle = win32con.WS_EX_TOPMOST # win32con.WS_EX_TOOLWINDOW | win32con.WS_EX_TOPMOST #| win32con.WS_EX_NOACTIVATE
        self.hwnd = win32gui.CreateWindowEx(exStyle, classAtom, "Taskbar Demo", style, \
                                          0, 0, win32con.CW_USEDEFAULT, win32con.CW_USEDEFAULT, \
                                          0, 0, hinst, None)

        win32gui.UpdateWindow(self.hwnd)

        icon = win32gui.LoadIcon(0, win32con.IDI_APPLICATION)
        self.setIcon(icon)
        self.show()

    def setIcon(self, hicon, tooltip=None):
        self.hicon = hicon
        self.tooltip = tooltip

    def showBaloon(self, title='标题', content='内容'):

        flags = win32gui.NIF_ICON | win32gui.NIF_MESSAGE | win32gui.NIF_INFO
        nid = (self.hwnd, 0, flags, win32con.WM_USER + 20, self.hicon, "", content, 10, title,
               win32gui.NIIF_INFO)

        win32gui.Shell_NotifyIcon(win32gui.NIM_MODIFY, nid)

    def show(self):
        """Display the taskbar icon"""
        flags = win32gui.NIF_ICON | win32gui.NIF_MESSAGE
        if self.tooltip is not None:
            flags |= win32gui.NIF_TIP
            nid = (self.hwnd, 0, flags, win32con.WM_USER + 20, self.hicon, self.tooltip)
        else:
            nid = (self.hwnd, 0, flags, win32con.WM_USER + 20, self.hicon)

        if self.visible:
            self.hide()
        win32gui.Shell_NotifyIcon(win32gui.NIM_ADD, nid)
        self.visible = 1

    def hide(self):
        """Hide the taskbar icon"""
        if self.visible:
            nid = (self.hwnd, 0)
            win32gui.Shell_NotifyIcon(win32gui.NIM_DELETE, nid)
        self.visible = 0

    def onDestroy(self, hwnd, msg, wparam, lparam):
        self.hide()
        win32gui.PostQuitMessage(0)  # Terminate the app.


if __name__ == '__main__':

    t = Taskbar()
    content = """
    auto_cv 说明:
    1. 按r绘制roi,绿色框线选者区域
    2. 按t绘制tpl,红色框线截图
    3. 按f绘制offset位置,红色点
    按esc退住出绘制,按c清除绘制,按s重新截图
    """
    t.showBaloon(title='截图提示', content=content)
    time.sleep(3)

 2.方法二:win10toast

from win10toast import ToastNotifier
 
toaster = ToastNotifier()
toaster.show_toast('news1', 'i love 中森名菜!', icon_path='E:\idle.ico', duration=10)
toaster.show_toast('news2', 'i love 中森名菜!', icon_path='E:\idle.ico', duration=10)